Archived initial release based on a time-dependent integration of VTI and PI during the first 3 ICU days
Background
Macrocirculatory flow and microcirculatory perfusion are related but not interchangeable.
In this framework, left ventricular outflow tract velocity–time integral (VTI) is used as a
surrogate of global flow, whereas perfusion index (PI) reflects peripheral perfusion.
Their contemporaneous combination defines four macro–micro circulatory states.
State Definitions
Concordant high-flow: VTI ≥ 16.9 and PI ≥ 1.2
Macro-predominant mismatch: VTI < 16.9 and PI ≥ 1.2
Micro-predominant mismatch: VTI ≥ 16.9 and PI < 1.2
This tool is intended for research, educational, and hypothesis-generating purposes only.
It is not designed for clinical decision-making or patient management.
Data Privacy
No input data are stored, transmitted, or shared.
All calculations are performed locally in the user's browser.
Methodological Note
The classification and trajectory rules are based on a conceptual macro–micro circulatory framework
and are intended for demonstration purposes.
Suggested Citation
Wang J, et al. A Time-Dependent Macro–Micro Circulatory Framework for Prognosis in Critical Illness. (in preparation)